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Publications 2005 - 2006

Brendler-Schwaab S, Hartmann A, Pfuhler St, Speit G

The in vivo comet assay: use and status in genotoxicity testing. Mutagenesis 2005, Volume 20, No 4: 245-254.

Burns A, O'Brien J, Auriacombe S, Ballard C, Broich K et al.

Clinical practice with antidementia drugs: a consensus statement from British Association for Psychopharmacology. Journal of Psychopharmacology 20, 2006, 732-755.

Claaßen S, Zünkler BJ

Comparison of the effects of metoclopramide and domperidone on HERG channels. Pharmacology 74, 2005, 31-36.

Frötschl R, Weickardt S, Staszewski S, Kaufmann G, Kasper P

Effects of chlorpromazine with and without UV irradiation on gene expression of HEPG2 cells. Mutation Research 575 , 2005, 47-60.

Gauthier S, Reisberg B, Zaudig M, Petersen RC, Ritchie K, Broich K et al.

Mild cognitive impairment. The Lancet 367, 2006, 1262-1270.

Guarro J, Kantarcioglu AS, Horré R, Rodriguez-Tudela JL, Cuenca-Estrella M, Berenguer J, de Hoog GS

Scedosporium apiospermum: Changing clinical spectrum of a therapy-refractory opportunist. Medical Mycology 44, 2006, 295-327.

Heim HK, Broich K

Selective COX-2 inhibitors and risk of thromboembolic events - regulatory aspects. Journal of Thrombosis and Haemostasis 96, 2006, 423-432.

Heinz BC, von Mallek D

Survey of incidents associated with hip and knee replacement devices. Analysis of the surveillance and registration system for medical products for the years 2000-2002.
Orthopäde 34, 2005, 47-54.

Heissig H, Urban KA, Hastedt K, Zünkler BJ, Panten U

Mechanism of the insulin-releasing action of α-ketoisocaproate and related α-keto acid anions. Molecular Pharmacology 68, 2005, 1097-1105.

Hofmann H, Choi SM, Wilsmann-Theis D, Horré R, Bieber T, de Hoog GS

Phialophora verrucosa causing invasive chromoblastomycosis and sinusitis in a child from northern Africa. Mycoses 48, 2005, 456-461.

Höschele D

Cell culture models for the investigation of NRTI-induced mitochondrial toxicity. Relevance for the prediction of clinical toxicity. Toxicology in Vitro 20, 2006, 535-546.

Höschele D, Wiertz M, Garcia-Moreno I

Investigating mitochondrial toxicity of nucleoside reverse transcriptase inhibitors and ethidium bromide in HepG2 cells. Archives of Pharmacology 2006, 372 (Suppl 1), No 386: 103.

Höschele D, Garcia-Moreno M, Wiertz I

Investigating mitochondrial toxicity of nucleoside reverse transcriptase inhibitors and ethidium bromide in HepG2 cells. ALTEX 23, 2006, 98.

Kasper P, Aeby P, Brendler-Schwaab S, Epe B, Frötschl R, Hertel C, Kirchner S, Liebsch M, Meurer K, Plappert-Helbig U, Schmidt E

Photo comet assay and photo micronucleus test in vitro:Contributions to the validation in a collaborative study. 35th Annual Meeting of the European Environmental Mutagen Society, 2005, Kos, Greece.

Kasper P, Aeby P, Brendler-Schwaab S, Epe B, Frötschl R, Hertel C, Kirchner S, Liebsch M, Meurer K, Plappert-Helbig U, Schmidt E

Assessment of the performance of in vitro photo-genotoxicity assays:Results of a collaborative study with 13 coded test chemicals. 5th World Congress on Alternatives & Animal Use in the Life sciences , 2005, Berlin.

Kasper P, Oliver G, Silva Lima B, Singer T and Tweats D

The emerging use of omic tech-nologies for regulatory non-clinical safety testing. Pharmacogenomics 6, 2005, 181-184.

Kopplow K, Wayss K, Enzmann H, Mayer D

Dehydroepiandrosterone causes hyperplasia and impairs regeneration in rat liver. International Journal of Oncology 27, 2005, 1551-1558.

Matthies A, Reinhardt M, Palmedo H, Ezziddin S, Abramowski B, Kuhn W, Biersack HJ, von Mallek D

Tc-99m labelled anti CD 66 antigranulocyte antibody imaging for assessment of bone marrow reserve. Cancer Invest. 23 (2), 2005, 199-122.

Möller HJ, Grunze H, Broich K

Do recent efficacy data on the drug treatment of acute bipolar depression support the position that drugs other than antidepressants are the treatment of choice? A conceptual review. European Archives of Psychiatry and Clinical Neuroscience 256, 2006, 1-16.

Mursch K, Trnovec S, Ratz H, Hammer D, Horré R, Klinghammer A, de Hoog GS, Behnke-Mursch J

Successful treatment of multiple Pseudallescheria boydii brain abscesses and ventriculitis/ependymitis in a 2-year-old child after near-drowning. Childs Nervous System 22, 2006, 189-192.

Reinhardt MJ, Biermann K, Wissmeyer M, Juengling FD, Brockmann H, von Mallek D, Ezziddin S, Joe AY, Krause TM

Dose selection for radioiodine therapy of borderline hyperthyroid patients according to thyroid uptake of (99m)Tc-pertechnetate: applicability to unifocal thyroid autonomy? European Journal of Nuclear Medicine and Molecular Imaging 33 (5), 2006, 608-612.

Sachs B, Merk HF

Cutaneous manifestations of drug allergies
Klinik, Pathophysiologie und Therapie kutaner Manifestationsformen. Hautarzt 56, 2005, 8-15.

Sachs B, Riegel S, Seebeck J, Beier R, Schichler D, Barger A, Merk HF and Erdmann S

Fluoroquinolone-Associated Anaphylaxis in Spontaneous Adverse Drug Reaction Reports in Germany. Drug Safety 29 (11), 2006, 1087-1100.

Siekmeier R, Lütz J

Safety of lay use products for monitoring of blood glucose - German Experience with the European vigilance system for in vitro diagnostic medical devices. Clinical Chemistry and Laboratory Medicine 2006, 44: A 191.

Symoens F, Garcia-Hermosa D, Robert V, Dannaui E, de Hoog GS, Horré R

The Pseudallescheria Database and Culture Collection; Trends in Medical Mycology (TIMM). Mycoses 2005, 48 (Suppl 2): 1-173.

Tarazona JV, Buzby ME, Hartmann A, Housenger JE, Olejniczak K, Sager N, Servos MR, Tolson ND

Scientific Basis for Aquatic Environmental Risk Assessment of Human Pharmaceuticals. Williams (Hrsg). Human Pharmaceuticals: Assessing the impacts on aquatic ecosystems. Pensacola (FL), USA: Societys of Environmental Toxicology and Chemistry, 2005, 269-298.

Valentin JP, Bass AS, Atrakchi A, Olejniczak K, Kannosuke F

Challenges and Lessons Learned Since Implementation of the Safety Pharmacology Guidance ICH S7A. Journal of Pharmacological and Toxicological Methods 52, 2005, 22-29.

Zobel A, Joe A, Freymann N, Clusmann H, Schramm J, Reinhardt M, Biersack HJ, Maier W, Broich K et al.

Changes in regional cerebral blood flow by therapeutic vagus nerve stimulation in depression: an exploratory approach. Psychiatry Research 139, 2005, 165-179.

Zünkler BJ

Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects. Pharmacology & Therapeutics 112, 2006, 12-37.

Zünkler BJ, Claaßen S, Wos-Maganga M, Rustenbeck I, Holzgrabe U

Effects of fluoroquinolones on HERG channels and on pancreatic ß-cell ATP-sensitive K+ channels. Toxicology 228, 2006, 239-248.